ScienceDaily (Sep. 6, 2009) — Can't sleep at night? A new study published in the journal Sleep has found that people who suffer from insomnia have heightened nighttime blood pressure, which can lead to cardiac problems. The investigation, which measured the 24-hour blood pressure of insomniacs compared to sound sleepers, was conducted by researchers from the Université de Montréal, its affiliated Hôpital du Sacré-Cœur de Montréal Sleep Disorders Centre and the Université Laval.
     "Over many years, chronic insomnia can have negative effects on the hearts of otherwise healthy individuals," says lead author Paola A. Lanfranchi, a professor in the Université de Montréal Faculty of Medicine and researcher at the Hôpital du Sacré-Cœur de Montréal Sleep Disorders Centre. "Whereas blood pressure decreases in regular sleepers and gives their heart a rest, insomnia provokes higher nighttime blood pressure that can cause long-term cardiovascular risks and damage the heart."
      The findings are important given that insomnia, which is a chronic difficulty falling or staying asleep, affects up to 48 percent of the population at some point in their lives. As part of the study, the scientific team recruited 13 otherwise healthy chronic insomniacs and 13 good sleepers. Subjects spent 40 hours in the sleep laboratory: two nights for adaptation and one for monitoring followed by the intervening day.
      "Blood pressure cycles are mainly linked to the sleep-wake cycle," says co-author Jacques Montplaisir, a professor in the Université de Montréal Department of Psychiatry and director of Hôpital du Sacré-Cœur de Montréal Disorders Center. "Since blood pressure is heightened among insomniacs, those with overt cardiac disease are particularly at risk for progression of the disease."
      The article "Nighttime Blood Pressure in Normotensive Subjects With Chronic Insomnia: Implications for Cardiovascular Risk," published in Sleep was authored by Paola A. Lanfranchi, Marie-Hélène Pennestri, Lorraine Fradette, Marie Dumont and Jacques Montplaisir of the Université de Montréal and its affiliated Hôpital du Sacré-Cœur de Montréal, as well as Charles M. Morin of the Université Laval.
     This study was funded by the Canadian Institutes of Health Research, the Heart and Stroke Foundation of Québec and the Fonds de Recherche en Santé du Québec.

失眠对心脏的危害-升高血压

      每日科学（2009年9月6日）——夜晚不能入睡？发表在睡眠杂志上一项新的研究发现失眠的人群会升高夜间血压，这会引起心脏的疾病。测量失眠者24小时血压，并与酣睡者相比较，是由蒙特利尔大学附属蒙特利尔圣心医院睡眠障碍中心和拉瓦尔大学的研究者进行的调查研究。
       “过了许多年，慢性失眠症可以对原本正常人的心脏有负面作用，”主要作者保拉兰弗兰基说，他是蒙特利尔大学医学院的教授和蒙特利尔圣心医院睡眠障碍中心的研究员。“但是在规律睡眠者血压会下降，让他们心脏休息一下，而失眠会更加升高夜间血压，会导致长期心血管风险和损伤心脏。”
    这些发现很重要，因为慢性很难入睡或保持睡眠的失眠在一些方向影响了48%人群的生活。作为研究的一部分，科学小组招募了13原本健康的慢性失眠者和13个睡眠良好者。项目在睡眠实验室花了40小时：两个晚个适应和一个晚上及中间一天监测。
         “血压循环主要和睡眠周期有联系，”共同研究者Jacques Montplaisir，是蒙特利尔精神病科的教授和蒙特利尔圣心医院疾病中心主任。“自失眠者血压会升高，他们会伴随着明显心脏疾病，尤其是处在这些疾病进展的风险中。”
         文章“患慢性失眠症血压正常的患者夜间血压：导致心血管风险，”发表在睡眠杂志，是由蒙特利尔大学和附属蒙特利尔圣心医院的Paola A. Lanfranchi, Marie-Hélène Pennestri, Lorraine Fradette, Marie Dumont and Jacques Montplaisir，还有拉瓦尔大学的Charles M. Morin共同撰写的。
    研究由加拿大健康研究学院、魁北克心脏和卒中基金会和魁北克健康研究基金资助。
         新研究显示患失眠症的人群会升高夜间血压，可以导致心脏疾病。